🧓 Is gravity ageing us?

PLUS: India’s GenAI moment has arrived

 

Good morning. It’s going to be a good day - let’s go after it 💪 

Ruchirr Sharma & Shatakshi Sharmaa  

TABLE OF CONTENTS

HEALTHCARE

Deepinder Goyal’s longevity startup, Continue, has introduced one of the boldest ideas in ageing science this year. The company suggests that gravity itself may be a hidden driver of how we age.

The basic idea

  • The brain sits above the heart, so blood has to travel upward against gravity.

  • Continue claims everyday upright posture can reduce blood flow to the brain by up to 17 percent.

  • Over decades, this steady reduction may weaken brain regions that regulate hormones, metabolism and essential bodily functions.

What we already know

  • Cerebral blood flow naturally drops by 20 to 40 percent between ages 20 and 80.

  • This decline has always been treated as a natural part of ageing.

  • Continue is asking whether gravity might be an early cause rather than a passive background force.

Clues from nature and human tradition

  • Animals like bats, sloths and flamingos often rest with their heads below their hearts and live longer than expected for their size.

  • Yoga traditions have used inverted poses for thousands of years.

  • Shorter people tend to live longer on average, possibly because their hearts pump against less gravitational distance.

What Continue is testing

  • The team built a device that measures brain blood flow continuously.

  • Early findings suggest inversions help:

    • Active yoga inversions improved blood flow by about 13 percent.

    • Passive inversion tables improved it by about 20 percent.

    • Simple legs up the wall gave a smaller but measurable boost.

  • A six week daily inversion study showed a 7 percent rise in average brain blood flow, which the company compares to reversing a decade of age related decline.

Where the research goes next

  • Continue says this is early science and gravity is only one possible contributor.

  • It has created a 25 million dollar research fund to support labs worldwide.

  • All data and methods are open source to invite independent validation, refinement or even refutation.

If gravity does play a role in ageing, it could reshape how we think about exercise, brain health, mood disorders and long term wellbeing. The question is far from settled, but Continue has ensured it will be studied seriously.

ARTIFICIAL INTELLIGENCE

Corporate India has quietly crossed a major AI milestone. Nearly half of Indian enterprises now run multiple Generative AI use cases in production, according to a new EY–CII report, while another 23 percent are still in pilot mode. This marks a clear shift from tinkering to tangible business impact.

Leaders are bullish about what comes next. Seventy six percent believe GenAI will significantly reshape their business, and sixty three percent say they feel ready to use it effectively. Companies are no longer limiting AI to side experiments. They are embedding it into core workflows where the value is measurable.

EY’s Mahesh Makhija puts it simply: India has moved beyond experimentation. The next step is designing systems where humans and AI agents work together smoothly. Companies that get this right, especially around data quality, model assurance, and Responsible AI, are expected to build the strongest competitive edge over the next decade.

Despite the enthusiasm, budgets still lag. Ninety five percent of firms spend less than one fifth of their IT budgets on AI. Only a small group, about four percent, have crossed the 20 percent mark. Leaders believe in AI, but most are still cautious with large-scale investment.

One thing is clear though. Speed has become the new currency. Ninety one percent of business leaders say rapid deployment is the biggest factor driving their choice between buying or building AI solutions.

Over the next year, enterprises plan to put their money into operations, customer service, and marketing, with AI talent shortages remaining a challenge across the board.

India’s AI landscape is no longer in early innings. It is at an inflection point, and the next twelve months will decide which companies pull ahead

GENERAL OVERVIEW

🗞️ Bite-sized summaries

🇶🇦 India Qatar Reset - External Affairs Minister S Jaishankar met Qatar’s top leadership in Doha to strengthen a partnership that covers energy, trade, investment, and regional cooperation. He held talks with Qatar’s Prime Minister and Foreign Minister Mohammed bin Abdulrahman bin Jassim Al Thani, reviewing progress in the Strategic Partnership and exchanging views on developments in West Asia and beyond. Jaishankar also called on Qatar’s Amir Sheikh Tamim bin Hamad Al Thani and reaffirmed India’s commitment to deeper ties. Both sides discussed new areas for collaboration as bilateral trade reached 14.08 billion dollars in 2023 to 2024, underscoring the importance of the relationship.

🧠 Warmer, Smarter AI - OpenAI’s GPT 5.1 shifts focus from pure capability to human-like interaction. The update introduces two model variants: Instant, which is warmer and better at following instructions, and Thinking, which handles complex tasks more persistently. It also adds eight personality presets such as Friendly, Candid, Nerdy and Cynical, addressing user feedback that GPT 5 felt too cold and transactional. This customization lets businesses tailor AI behavior to their brand and use-case, from formal compliance to creative marketing. GPT 5.1 signals a broader industry pivot toward AI that not only performs well but feels more natural, adaptable and engaging.

HEADLINES

🧑‍🍳 What else is cookin’?

What’s happening in India (and around the world 🌍️)

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That’s all for today folks - have a lovely day and we’ll see you tomorrow.